Title: Fermentation process for the preparation of L-amino acids using strains of the family enterobacteriaceae
Application Number: 01816550 Application Date: 2001.09.05
Publication Number: 1466630 Publication Date: 2004.01.07
Approval Pub. Date: 2006.03.22 Granted Pub. Date: 2006.03.22
International Classifi-cation: C12P13/04,C12P13/08,C12N1/21,C12N15/11,C12N15/60,C12P13/04,C12R1/19
Applicant(s) Name: Degussa AG Address:
Inventor(s) Name: M. Rieping, C. Bastuck
Attorney & Agent: lin xiaogong
Abstract:
     The invention relates to a fermentation process for the preparation of L-amino acids, especially L-threonine, in which the following steps are carried out: a) fermentation of the microorganisms of the family Enterobacteriaceae producing the desired L-amino acid, in which microorganisms at least the pckA gene and/or the open reading frames yjfA and ytfP are, individually or jointly, attenuated and, in particular, switched off, b) enrichment of the L-amino acid in the medium or in the bacterial cells, and c) isolation of the L-amino acid.
Time: 8