Title: Process for producing D-serine
Application Number: 01821625 Application Date: 2001.10.29
Publication Number: 1531599 Publication Date: 2004.09.22
Approval Pub. Date: 2006.10.18 Granted Pub. Date: 2006.10.18
International Classifi-cation: C12P41/00,C12N1/21,C12R1/19
Applicant(s) Name: Kyowa Hakko Kogyo Co., Ltd. Address:
Inventor(s) Name: Ikeda Hajime, Yonetani Yoshiyuki
Attorney & Agent: zhong shouqi meng fanhong
Abstract:
     The present invention relates to: a process for producing D-serine wherein a microbial cell which is modified to have a higher L-serine deaminase activity than Escherichia coli DH5 alpha strain, a culture of said cell, or a processed product thereof is brought into contact with DL-serine in a DL-serine-containing medium to decompose L-serine, and the remaining D-serine is recovered from the medium; and a microorganism used for this production process. D-serine is a useful compound as a synthetic intermediate for useful medicaments such as D-cycloserine.
Time: 5