Title: Human monoclonal antibody combination with cross protection action
Application Number: 87102167 Application Date: 1987.02.06
Publication Number: 1016129 Publication Date: 1988.02.03
Approval Pub. Date: Granted Pub. Date:
International Classifi-cation: A61K39/40;C12N15/00;C12Q1/04
Applicant(s) Name: Genetics System Co. Address:
Inventor(s) Name: Howard V. Ruff
Attorney & Agent: GU BAIDI
Abstract:
    Cell lines have been produced that secrete human monoclonal antibodies capable of binding to molecules of different bacterial species. These antibodies have been found to be protective against lethal challenges of various bacterial genera. Pharmaceutical compositions containing these antibodies, which can be in combination with other monoclonal antibodies, blood plasma fractions and antimicrobial agents, and the prophylactic and therapeutic use of such compositions in the management of infections are included.
Time: 7