Title: Method for screening compositions
Application Number: 93116853 Application Date: 1993.07.23
Publication Number: 1085255 Publication Date: 1994.04.13
Approval Pub. Date: Granted Pub. Date:
International Classifi-cation: C12N1/19;C12N15/11;C12N15/63;C12Q1/02
Applicant(s) Name: Smithkline Beecham Corporation Address:
Inventor(s) Name: Shelley Lynn Berger;Leonard Pershing Guarente;JR C
Attorney & Agent: WANG YANG
Abstract:
    This invention relates to a novel method for identifying potential antiviral drugs. A recombinant cell transformed with regulatable viral transactivating element is employed in screen to detect molecules capable of relieving inhibition caused by the expressed element. New classes of chemical entities can be identified that inhibit initiation of viral transcription.
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