Title: Reshaped monoclonal antibodies against an immunoglobulin isotype
Application Number: 93119845 Application Date: 1993.09.24
Publication Number: 1088986 Publication Date: 1994.07.06
Approval Pub. Date: 2002.01.23 Granted Pub. Date: 2002.01.23
International Classifi-cation: A61K39/395;A61K39/44;C12N15/12;C12N15/63;C12P21/08;C12Q1/68
Applicant(s) Name: CIBA-Geigy Ag Address:
Inventor(s) Name: Norman Hardman;Frank Kolbinger;Jose Saldanha
Attorney & Agent: HUANG GESHENG
Abstract:
    The invention relates to reshaped human monoclonal antibodies directed against isotypic determinants of immunoglobulin E (IgE), direct equivalents and derivatives of said antibodies. The molecules of the invention are useful for diagnostics, prophylaxis and treatment of allergy.
Time: 10