Title: PTP 1D, a novel protein tyrosine phosphatase
Application Number: 93114840 Application Date: 1993.10.06
Publication Number: 1091469 Publication Date: 1994.08.31
Approval Pub. Date: Granted Pub. Date:
International Classifi-cation: A61K37/02;A61K37/54;C07K13/00;C12N9/14;C12N15/55;C12N15/63;C12P21/02;C12P21/08;C12Q1/34;C12Q1/68
Applicant(s) Name: Max-Planck-Gesellschaft Zur Foerderung Der Wissens Address:
Inventor(s) Name: Axel Ullrich;Wolfgang Vogel
Attorney & Agent: WANG YANG
Abstract:
    A novel protein tyrosine phosphatase is the protein designated PTP 1D. The PTP 1D protein may be produced by recombinant means, for example using a nucleic acid construct encoding the protein as provided herein. Also disclosed is an antibody specific for an epitope of PTP 1D protein. Methods for identifying compounds which bind to a PTP 1D protein and inhibit or stimulate its enzymatic activity, pharmaceutical compositions comprising PTP 1D, and methods for treating a disease associated with PTP 1D protein using such compositions, are provided.
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