Title: Anti-urokinase monoclonal antibody, matrix bearing it, test method and biochemical test kits which use it
Application Number: 85107184 Application Date: 1985.09.27
Publication Number: 1003403 Publication Date: 1986.09.24
Approval Pub. Date: 1993.08.18 Granted Pub. Date: 1993.08.18
International Classifi-cation: A61K39/44;C12N15/06;G01N33/541;G01N33/577
Applicant(s) Name: Gruppo Lepetit S.P.A. Address:
Inventor(s) Name: Adolfo Soffientini;Giovanni Cassani;Maria Luisa No
Attorney & Agent: GU BAIDI XIN MINZHONG
Abstract:
    A class of new IgG1 monoclonal antibodies, directed to an epitope on human urokinase, which selectively bind to high molecualr weight urokinase (54,000), or a single-chain precursor thereof, without binding to low molecular weight urokinase (33,000) have an affinity constant for urokinase which is suitable for use in an immono-adsorption-based purification system and does not impair the enzymatic activity of urokinase. This antibody is also useful in immunoassays.
Time: 4
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