Title: Improved method for man-promoting growth factor C
Application Number: 86102889 Application Date: 1986.03.26
Publication Number: 1005298 Publication Date: 1986.11.26
Approval Pub. Date: 1997.04.16 Granted Pub. Date: 1997.04.16
International Classifi-cation: A61K38/30;C07K14/65;C12N15/16;C12N15/65
Applicant(s) Name: Biogen M.V. Address:
Inventor(s) Name: Jaly. N. Boole
Attorney & Agent: GU BAIDI XIN MINZHONG
Abstract:
    A process for selecting DNA sequences that are optimal for the production of polypeptides in hosts transformed with those DNA sequences. These DNA sequences, which code for a variety of human and animal proteins, permit the high level expression of those products in host cells. In the preferred embodiment of this invention, DNA sequences optimal for the production of human somatomedin C are selected and employed to express that growth enhancing factor.
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