Title: Process of the preparation of clavulanic acid and its salts and esters
Application Number: 85108444 Application Date: 1985.10.26
Publication Number: 1002149 Publication Date: 1986.08.06
Approval Pub. Date: 1991.07.31 Granted Pub. Date: 1991.07.31
International Classifi-cation: C12P17/18
Applicant(s) Name: Antibioticos S.A. Address:
Inventor(s) Name: Jose Luis Fernandez Puentes
Attorney & Agent: LIU YUANJIN
Abstract:
    At least part of the assimilable carbon source is added to the culture medium when producing clavulanic acid by fermenation with a producing micro-organism. The clavulanic acid is readily obtained in good yield and purity, preferably as an ester or salt in a form suited for formulation as pharmaceuticals.
Time: 5
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