Title: The process for D-2 amino acids
Application Number: 87108140 Application Date: 1987.12.17
Publication Number: 1021539 Publication Date: 1988.10.19
Approval Pub. Date: Granted Pub. Date:
International Classifi-cation: C12P13/04
Applicant(s) Name: Institute of Biology, Shanxi Province Address:
Inventor(s) Name: Luo Xiuhui
Attorney & Agent: NIE PUYANG
Abstract:
     D-alpha amino acids are those substances having optical activities some of them are very useful substances in medicine industry, such as D(-)phenyl-glycine and D(-)para hydroxyphenylglycine are all the important side chains of semi-synthetic antibiotics. The synthesis of them by the present chemical method shows that their optic resolution is relatively complex. The invention can transform the DL-5 heroin substance into D-alpha-amino acids by means of the resolution of microbe 2262 bacteria in one step. The yield, by this method, of D-hydroxyphenylglycine is about 75%, with a substratum concentration of 8.0%; while the yield of D(-)phenylglycine is about 75%, with a substratum concentration of 3.0%.
Time: 8
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