Title: Protein cross linking agent and method therefor
Application Number: 03105003 Application Date: 2003.02.28
Publication Number: 1524880 Publication Date: 2004.09.01
Approval Pub. Date: Granted Pub. Date: 2006.01.04
International Classifi-cation: C07K14/805,C07K14/76,C07K19/00,C07K1/107,C08H1/00
Applicant(s) Name: Institute of Process Engineering, Chinese Academy Address: 100080
Inventor(s) Name: Su Zhiguo, Xu Yuhong
Attorney & Agent:
Abstract:
     The invention provides a method for using homotype double functional cross linking agent with epoxy radicals for protein and polypeptide cross bonding, the cross linking agent used by the present invention can realize an ideal reaction velocity for the cross bonding between proteins and polypeptides with good controllability. When applied to the hemoglobin cross bonding under controlled conditions, the method can raise the yield for inter-molecule cross bonding to above 90%.
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