Title: Process for preparing polypeptide related to alpha-human afrial natriuretic polypeptide
Application Number: 85106564 Application Date: 1985.08.31
Publication Number: 1009516 Publication Date: 1987.03.18
Approval Pub. Date: Granted Pub. Date:
International Classifi-cation: A61K37/02,C07K7/04
Applicant(s) Name: Shionogi Address:
Inventor(s) Name: Ichikazu Nakao
Attorney & Agent: GU BAIDI XIN MINZHONG
Abstract:
     A polypeptide of the general formula R-Asn-Ser-Phe-Arg-Tyr-OH can be used for development of a agent for clinical diagnosis of primary hypertension and used to study its pathophysiology. In the formula, R is H, Cys, Gly-Cys, Leu-Gly-Cys, Gly-Leu-Gly-Cys, Ser-Gly-Leu-Gly-Cys, Gln-Ser-Gly-Leu-Gly-Gys, Ala-Gln-Ser-Gly-Leu-Gly-Cys, Gly-Ala-Gln-Ser-Gly-Leu-Gly-Gys, or Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys and its salts.
Time: 7