Title: Process for the production of new trifluoromethyl Ketone Substituted peptide derivatives
Application Number: 86101066 Application Date: 1986.01.22
Publication Number: 1004665 Publication Date: 1986.11.05
Approval Pub. Date: 1995.02.15 Granted Pub. Date: 1995.02.15
International Classifi-cation: A61K37/02;C07K5/02
Applicant(s) Name: ICI Americas Inc. (US) Concord pike Address:
Inventor(s) Name: Andrew; Stein;Bergeson;Diane Amy; Wildonger;John A
Attorney & Agent: LUO HONG
Abstract:
    The invention concerns pharmaceutically useful trifluoromethyl ketone substituted di-, tri- and tetra-peptide derivatives of the formulae Ia, Ib, Ic set out here:W after, and salts thereof, which are inhibitors of human leukocyte elastase. Also described herein are pharmaceutical compositions containing a peptide derivative and processes and intermediates for use in the manufacture of the peptide derivatives.
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