Title: Synthetic vaccines for foot and mounth disease
Application Number: 86103718 Application Date: 1986.06.02
Publication Number: 1008341 Publication Date: 1987.02.04
Approval Pub. Date: Granted Pub. Date:
International Classifi-cation: A61K39/135;C07K1/06;C12N15/42
Applicant(s) Name: Eli Lilly and Co. Address:
Inventor(s) Name: Gerald Stephen Brooke;Richard Dennis Dimarchi
Attorney & Agent: CAO HENGXING
Abstract:
    Compounds having activity in treating or preventing foot and mouth disease are disclosed. The compounds contain a sequence of the formula X-A-Y-B-Z in which A and B are amino acid residue sequences comprising sequences of the foot-and-mouth disease virus VP1 capsid protein serotypes, one of which contains from 18 to 24 amino acid residues and includes the amino acid residue sequence in positions 141 to 158 of the O serotype or the equivalent sequence of other serotypes and the other of which contains from 14 to 20 amino acid residues and includes the amino acid residue sequence in positions 200 to 213 of the O serotype or the equivalent sequence of other serotypes; X, Z and Y are defined in the description.
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