Title: Method of chain combination
Application Number: 87104447 Application Date: 1987.06.23
Publication Number: 1016328 Publication Date: 1988.02.10
Approval Pub. Date: 1995.09.20 Granted Pub. Date: 1995.09.20
International Classifi-cation: A61K38/08;A61K38/22;C07K7/16
Applicant(s) Name: Genentech, Inc. (US) 460 Point San Bruno Blvd, Sou Address:
Inventor(s) Name: John Perry Barnier;Paul Douglao Johnston
Attorney & Agent: WANG SUNJIA
Abstract:
    Production of human relaxin or novel human relaxin analogs by combination of a human relaxin A-chain and B-chain comprises combining the reduced form of the human relaxin A-chain and the reduced form of the human relaxin B-chain in an aqueous medium having a pH of about 7.0 to 12 at room temperature, under conditions that are mildly denaturing for the relaxin B-chain such that the human relaxin or novel human relaxin analog can be formed.
Time: 9
<- Previous Patent:Method of preparing toxoid   |  Next Patent:Stable pharmaceutical preparation... ->