Title: Method of preparing mammal cell kinetin synthesis inhibitoroy factor
Application Number: 200610099742 Application Date: 1990.06.27
Publication Number: 1982459 Publication Date: 2007.06.20
Approval Pub. Date: Granted Pub. Date:
International Classifi-cation: C12N15/12;C12N15/63;C12N15/85;C12P21/02;C07K14/435;C07K16/18;A61K38/17;A61K39/395;A61P37/00
Applicant(s) Name: Schering Corp. Address:
Inventor(s) Name: Mosmann Timothy R.;Moore Kevin W.;Bond Martha W.;V
Attorney & Agent: liangmou
Abstract:
    Mammalian genes and proteins, designated cytokine synthesis inhibitory factors (CSIFs), are provided which are capable of inhibiting the synthesis of cytokines associated with delayed type hypersensitivity responses, and which, together with antagonists, are useful in treating diseases associated with cytokine imbalances, such as leishmaniasis and other parasitic infections, and certain immune disorders including MHC associated autoimmune diseases caused by excessive production of interferon- gamma .
Time: 5