Title: Method for preparing mammal cell kinetin synthetic inhibitory factor
Application Number: 01112406 Application Date: 1990.06.27
Publication Number: 1317569 Publication Date: 2001.10.17
Approval Pub. Date: 2007.05.30 Granted Pub. Date: 2007.05.30
International Classifi-cation: C12N15/12;C12P21/02;C07K14/435
Applicant(s) Name: Schering Corp Address:
Inventor(s) Name: Timofi R. Mosman;Kavin W. Mull;Marta W. Band
Attorney & Agent: tan mengsheng
Abstract:
    Mammalian genes and proteins, designated cytokine synthesis inhibitory factors (CSIF), are provided which are capable of inhibiting the synthesis of cytokines associated with delayed type hypersensitivity responses, and which, together with antagonists, are useful in treating diseases associated with cytokine imbalances, such as leishmaniasis and other parasitic infections, and certain immune disorders including MHC associated autoimmune diseases caused by excessive production of interferon-gamma .
Time: 6