Title: Novel nucleic acid trangsfer agents, compsns, contg. same and uses
Application Number: 99804274 Application Date: 1999.03.30
Publication Number: 1294582 Publication Date: 2001.05.09
Approval Pub. Date: Granted Pub. Date:
International Classifi-cation: A61K31/47;C07D233/48;C07D239/14;C07J41/00;C07K5/06;C12N15/87
Applicant(s) Name: Aventis Medicines S.A. Address:
Inventor(s) Name: G. Byk;M. Frederic;H. Hofland
Attorney & Agent: chen wenbeng
Abstract:
    The invention concerns novel compounds useful as agents for transferring nucleic acids into cells. Said novel compounds are more particularly related to the lipopolyamine family, and comprise at least a cyclic amidine function. They are useful for transfecting nucleic acids of interest into different cell types, in vitro as well as in vivo or ex vivo.
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