Title: Process for preparing S-adenosyl-L-methionine and stable salts with polyanions
Application Number: 85107218 Application Date: 1985.09.28
Publication Number: 1002869 Publication Date: 1986.09.03
Approval Pub. Date: 1992.03.11 Granted Pub. Date: 1992.03.11
International Classifi-cation: A61K31/70;C07H19/16
Applicant(s) Name: Gibipharma S.P.A. Address:
Inventor(s) Name: Vincenzo Zappia
Attorney & Agent: XU RUXUN LIU MENGMEI
Abstract:
    Stable salts of S-adenosyl-L-methionine with water-soluble polyanions, such as polyphosphates, polyvinylsulfonates -sulfates or -phosphates, polyacrylates, polystyrene sulfonates, are described. The salts according to the invention, prepared by precipitation from aqueous solutions of pH not exceeding 3.5, possess peculiar stability, solubility, nonhygroscopicity and are valuable for use as active constituents in pharmaceutical compositions.
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