Title: Composition and method for stabilization of dinucleotides
Application Number: 87100939 Application Date: 1987.02.23
Publication Number: 1014370 Publication Date: 1987.11.04
Approval Pub. Date: 1993.10.06 Granted Pub. Date: 1993.10.06
International Classifi-cation: C07H21/02;C12Q1/00
Applicant(s) Name: Abbott Laboratories Address:
Inventor(s) Name: David A. Yost
Attorney & Agent: LUO CAIXI
Abstract:
    A reduced dinucleotide, preferably nicotinamide adenine dinucleotide (NADH), is stabilized in an aqueous base liquid containing propylene glycol, boric acid and a buffer capable of buffering within a pH range of 8-11. The stabilized liquid contains greater than 50% (v/v) water. The remaining volume contains propylene glycol which has been chemically treated to remove oxidants. This reagent may be used by itself or in conjunction with an assay reagent system for use in the clinical laboratory.
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