Title: Process and composition for purification of amphotericin B
Application Number: 90100998 Application Date: 1990.01.31
Publication Number: 1053794 Publication Date: 1991.08.14
Approval Pub. Date: Granted Pub. Date: 1995.08.30
International Classifi-cation: C07H1/06,C07H17/08
Applicant(s) Name: E.R. Squibb Address:
Inventor(s) Name: Elizabeth Bryan, Gerd W. Michel
Attorney & Agent: YANG JIUCHANG
Abstract:
     A unique four-solvent system comprising methanol, dimethylformamide, methylene chloride and water is employed to provide an improved process for the purification and crystallization of amphotericin B.
Time: 8