| Title: | Process for preparing diterpene alkaloid and its medicinal usage | ||
| Application Number: | 93110509 | Application Date: | 1993.01.01 |
| Publication Number: | 1088827 | Publication Date: | 1994.07.06 |
| Approval Pub. Date: | Granted Pub. Date: | 1998.07.22 | |
| International Classifi-cation: | A61K35/78,C07G5/00 | ||
| Applicant(s) Name: | China College of Pharmacology | Address: | 210009 |
| Inventor(s) Name: | Liu Jinghan, Hou Dehui | ||
| Attorney & Agent: | |||
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Abstract: |
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| A process for preparing diterpene alkaloid includes solvent extraction of aconitum coreanum, a Chinese-medicinal herb, recovery of liquid extrat, making extract dissolve in acidic water, coloidal eduction, removing recipitate, degreasing with organic solvent, removing organic solvent, alkalifying acidic water to pH 5-10, extraction with organic solvent, recovering organic solvent to obtain coarse coreanine A, recrystallizing repeatedly from organic solvent, column chromatography and drying at 50-100 deg.C to obtain refined coreanine A product, which and whose salt may be made into medicine for treating or preventing cardiovascular diseases. | |||
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| Time: | 10 | ||
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