Title: Derivatives of taxol, pharmaceutical compositions thereof and methods for the preparation thereof
Application Number: 90104682 Application Date: 1990.07.13
Publication Number: 1058018 Publication Date: 1992.01.22
Approval Pub. Date: Granted Pub. Date:
International Classifi-cation: A61K31/335,C07D305/14
Applicant(s) Name: University of Kansas Address:
Inventor(s) Name: Abraham E. Mathew
Attorney & Agent: QUAN GYONGLIU
Abstract:
     Derivatives of taxol are provided together with pharmaceutical compositions of such derivatives. The taxol derivatives have increased water solubility as compared to taxol, and have excellent antitumor activity.
Time: 3