Title: Preparation of alcohol-extended and amine-extended piperazines
Application Number: 90109981 Application Date: 1990.12.10
Publication Number: 1062351 Publication Date: 1992.07.01
Approval Pub. Date: Granted Pub. Date:
International Classifi-cation: C07D241/04
Applicant(s) Name: The Dow Chemical Co. Address:
Inventor(s) Name: David C. Molzahn, George E. Hartwell
Attorney & Agent: YANG HOUCHANG
Abstract:
     A process for preparing alcohol-extended and amine-extended piperazines comprising contacting a difunctional aliphatic alcohol with a reactant amine, wherein at least one of the aliphatic alcohol or the reactant amine contains a piperazine moiety, in the presence of a catalyst containing a tungsten heteropoly acid. For example, monoethanolamine reacts with piperazine in the presence of a 12-tungstophosphoric acid catalyst to yield predominately N-(2-aminoethyl) piperazine, which is an amine-extended piperazine.
Time: 8