Title: 1,5-benzodiazepine derivatives having CCK antagonistic or agonistic activity
Application Number: 94191773 Application Date: 1994.04.14
Publication Number: 1120843 Publication Date: 1996.04.17
Approval Pub. Date: 2000.11.15 Granted Pub. Date: 2000.11.15
International Classifi-cation: A61K31/55;C07D243/12;C07D403/12
Applicant(s) Name: Glaxo Inc. Address:
Inventor(s) Name: Elizabeth Ellen Sugg;Christopher Joseph Aquino;Jer
Attorney & Agent: GUAN LIXIN LUO CAIXI
Abstract:
    Novel benzodiazepine compounds of formula (1) which exhibit agonistic activity for CCK-A receptors enabling them to modulate the hormones gastrin and cholecystokinin (CCK) in mammals for use in medicine as anorectic agents in the regulation of appetite, the treatment of obesity and the maintenance of weight loss.
Time: 5