Title: Solventless process for making 2, 6 -difluorobenzonitrile
Application Number: 95197478 Application Date: 1995.11.17
Publication Number: 1174546 Publication Date: 1998.02.25
Approval Pub. Date: Granted Pub. Date:
International Classifi-cation: C07C253/30;C07C255/50
Applicant(s) Name: Dowelanco Address:
Inventor(s) Name: M. W. Zettler;R. E. Tobey;R. B. Leng
Attorney & Agent: FAN WEIMIN
Abstract:
    A process for making 2,6-difluorobenzonitrile, comprising reacting 2,6-dichlorobenzonitrile with a substantially anhydrous metal fluoride at a temperature between about 160 DEG C. and about 300 DEG C. and in the presence of a phase transfer catalyst, which is typically a polyether, tetra-substituted phosphonium salt, tetra-substituted ammonium salt, and cryptand, but in the absence of a solvent. After taking off the product the resulting mixture may be recycled into the reactor for the next reaction cycle. Upon build-up of tars in the reaction process, the invention includes the separation of catalyst from the tars and the recycle thereof.
Time: 9