Title: Preparation of cinnamate sunscreen agents
Application Number: 95196863 Application Date: 1995.12.01
Publication Number: 1170401 Publication Date: 1998.01.14
Approval Pub. Date: 2002.05.01 Granted Pub. Date: 2002.05.01
International Classifi-cation: C07C69/76
Applicant(s) Name: ISP Van Dyk Inc. Address:
Inventor(s) Name: A. Alexander;R. K. Chaudhuri
Attorney & Agent: LIN YUNHE
Abstract:
    This invention relates to an improved process for the manufacture of cinnamate compounds. The process comprises: (a) dissolving a C1 to C4 alkoxy benzaldehyde and a C1 to C4 alkyl acetate in a common hydrocarbon solvent; (b) reacting the resulting solution in the presence of a strong alkali metal-containing base under mild conditions; (c) acidifying the resulting mixture; (d) esterifying said acetic acid and stripping the resulting acetic acid ester from the mixture; (e) reacting the remaining C1 to C4 alkyl C1 to C4 alkoxycinnamate and C1 to C4 alkoxycinnamic acid with a C5 to C14 alkanol in the presence of said strong polybasic acid alkali metal salt suspension; and (f) recovering the product. The process of the invention improves the purity of the efficiency of producing and the product.
Time: 3