Title: Process for preparing deuterated organic compounds
Application Number: 88100364 Application Date: 1988.01.15
Publication Number: 1020232 Publication Date: 1988.08.17
Approval Pub. Date: Granted Pub. Date:
International Classifi-cation: C07B59/00;C07C13/42;C07C15/46;C07C31/38;C07C39/04;C07C57/04;C07C69/54;C07C121/48
Applicant(s) Name: Hoechst AG Address:
Inventor(s) Name: Peter Wigener
Attorney & Agent: WU DAJIAN QUAN JING
Abstract:
    The process for the preparation of deuterated acrylic acid or methacrylic acid by direct exchange of hydrogen by deuterium from D2O in the presence of a catalyst, which is hitherto known, is time-consuming and requires a large excess of D2O. Deuterated compounds are obtained in good yield with small amounts of D2O in a very short reaction time by using hydrogenation or (de)hydrating catalysts based on palladium, nickel and copper and high reaction temperature. The novel process can also be used for readily-polymerisable monomers without it being necessary for a polymerisation inhibitor to be present.
Time: 8